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Researchers Discover the Molecular Roots of Alzheimer’s Disease

Alzheimer’s disease is a neurodegenerative condition that is still not fully understood by the medical community worldwide. Scientists continue to conduct ambitious research to find effective treatment options for this common form of dementia. Pawleys Island in-home senior care professionals would like to share a study on Alzheimer’s disease recently completed by the Washington University School of Medicine in Missouri.

This prestigious institution of higher education analyzed the molecular structure of the TREM2 protein. The enzyme removes cellular waste in the brain and other parts of the nervous system. A structural change of TREM2 can lead to gradual deterioration in cognitive capabilities. The brain loses its normal function if excessive waste accumulates over time. For example, the amyloid beta amino acids tend to build up if there isn’t significant TREM2 activity. People who have moderate to severe Alzheimer’s disease often show very high levels of amyloid beta, which is a type of plaque comparable to cholesterol in the arteries.

Researchers at the Washington University School of Medicine were particularly curious about the mutation of TREM2 on a molecular scale. There isn’t any clear evidence to identify specific factors that can lead to alteration of this protein. Some experts believe genetics may play a key role in the formation and function of TREM2 throughout a person’s life. However, there is no strong evidence that marks any form of dementia as a hereditary disease. Aging naturally increases the risk for Alzheimer’s disease and other similar conditions like Parkinson’s disease. To prevent or slow the progression of these neurological conditions, scientists need to understand the molecular behavior of TREM2 and other relevant enzymes. A cure for Alzheimer’s disease would be based on a medication that can alter the composition of this important protein.

If your senior loved one has Alzheimer’s and you require assistance to take care of him or her, reach out to Home Care Assistance. In addition to part-time and live-in care, we offer specialized dementia and Alzheimer’s care. Pawleys Island, SC, seniors can also benefit from our proprietary Cognitive Therapeutics Method (CTM), which was designed to help boost brain health. For more information on CTM and our other senior care services, call one of our experienced Care Managers today at (843) 353-3105.